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Effects of two-year vitamin B12 and folic acid supplementation on depressive symptoms and quality of life in older adults with elevated homocysteine concentrations: additional results from the B-PROOF study, an RCT

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Having the shot directly in to the muscle allows the liquid vitamin to enter the blood stream quickly, bypassing the digestive system and the gastric acids and many other obstacles anything which is taken via the mouth has to go through to reach the small intestine, for re absorption

I like the Pascoe most because I have almost no pain using them